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Using MPC for Anonymous and Private DNA Analysis

10 months ago
  • #MPC
  • #genomics
  • #privacy
  • Monadic DNA conducted an experiment to allow anonymous and private access to genetic data.
  • Thirty participants provided saliva samples at an event in Denver, using a Web app to claim their genotyping results with a unique kit ID and PIN.
  • Data was uploaded to encrypted storage using Nillion’s MPC technology, enabling computations without exposing raw genomic data.
  • Sample collection occurred during ethDenver, with participants providing samples and choosing a PIN for data claim.
  • Participants were interested in POAPs, and many had never had their DNA analyzed before due to privacy concerns.
  • Samples were shipped to Autogen for lab processing, using the Global Screening Array for genotyping (~500k markers per participant).
  • Data was shared by the lab in encrypted files, stored in DigitalOcean Spaces, and claimed by participants via the Web app.
  • MPC was used for encrypted storage and analysis, ensuring data remained private during computation.
  • The experiment successfully demonstrated the feasibility of MPC for genomic analysis, with participants satisfied with the results.
  • Future work includes improving anonymity with wetware solutions, zero-knowledge proofs, and combining FHE with MPC for robust privacy.