Chikungunya virus: global epidemiology, transmission dynamics, and emerging challenges for public health - PubMed
6 hours ago
- #Public Health
- #Arbovirus
- #Chikungunya virus
- Chikungunya virus (CHIKV) has resurged globally over the last two decades, becoming a major public health concern.
- Key drivers of spread include viral mutations (e.g., E1-A226V), urbanization, climate change, and expansion of Aedes mosquito habitats.
- Despite the approval of two vaccines, challenges remain regarding long-term safety, immunogenicity, cost, and equitable access in low-resource regions.
- Clinical similarities with dengue and Zika complicate accurate diagnosis and surveillance, underscoring the need for improved diagnostic methods.
- Addressing CHIKV requires enhanced genomic and vector surveillance, cross-disciplinary risk prediction, and cooperative prevention strategies within a 'One Health' framework.