Surveillance and vaccine effectiveness of pertussis, the Netherlands, 2012 to 2024, with an unprecedented surge in 2023 and 2024 - PubMed

3 days ago

Pertussis notifications dropped during the COVID-19 pandemic, from around 6,000 in 2013-19 to 79 in 2021.
A surge occurred from May 2023, peaking in March 2024, resulting in 18,208 notifications in 2024.
Notifications and hospitalizations in 2024 were highest among infants aged 0-5 months.
In 2023-24, 10 deaths were reported, including 6 infants and 4 individuals aged 60 or older.
83% of mothers of notified infants aged 0-2 months in 2024 were unvaccinated.
Maternal vaccine effectiveness against pertussis in infants aged 0-2 months was 91% from 2020-24.
Primary series vaccine effectiveness was high, declining over time: 98% at age 1, 92% at age 3, 92% post-booster at age 5, and 71% at age 9.
Infant vaccination uptake decreased from 95% in 2011 to around 86% in 2024.
Maternal vaccination was introduced in 2019, with uptake around 70%.
Low population immunity after reduced circulation contributed to the highest pertussis incidence ever recorded in the Netherlands.

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