Exploring Neuronal Exosome miRNAs as Biomarkers of Neuroinflammation and Neuroplasticity in Amateur Boxers After Repetitive Head Trauma - PubMed
5 hours ago
- #Biomarkers
- #Sports-related brain injury
- #Neuroinflammation
- Study explores neuron-derived exosomal miRNAs as biomarkers for neuroinflammation and neuroplasticity in amateur boxers after repetitive head trauma.
- Repetitive mild traumatic brain injuries in contact sports like boxing are risk factors for long-term neurodegenerative conditions.
- Neuron-derived exosomes were isolated from plasma samples before and after sparring sessions in ten male athletes.
- Eight miRNAs related to neuroplasticity and inflammation were analyzed, showing significant changes post-sparring.
- Findings suggest neuron-derived exosomal miRNAs could serve as peripheral biomarkers for early detection of sports-related brain injury.
- The study was approved by the Ethics Committee and conducted in accordance with the Declaration of Helsinki.