Efficacy and safety of Dysmenorrhea Patch acupoint application in women with primary dysmenorrhea: a randomized double-blind controlled trial - PubMed
5 hours ago
- #randomized controlled trial
- #primary dysmenorrhea
- #acupoint application
- The study evaluates the efficacy and safety of Dysmenorrhea Patch acupoint application in women with primary dysmenorrhea (PD).
- A randomized, double-blind, placebo-controlled trial was conducted with 110 participants aged 18-40 years.
- Participants used the Dysmenorrhea Patch or a placebo for three consecutive menstrual cycles, applied during the non-menstrual phase.
- Primary endpoint was the total effective rate (TER) based on Numerical Rating Scale (NRS) score reduction.
- Secondary endpoints included pain intensity, TCM syndrome scores, prostaglandin levels, and safety outcomes.
- Results showed a significantly higher TER in the intervention group (60.00%) compared to the control group (34.55%).
- The intervention group had lower NRS pain intensity, improved TCM syndrome scores, and better prostaglandin balance.
- No adverse events or ALT abnormalities were observed, indicating good safety.
- The study concludes that Dysmenorrhea Patch is effective and safe for PD management, but larger long-term studies are needed.