Harnessing genomics for early cancer detection, risk stratification and prevention - PubMed
6 hours ago
- #cancer genomics
- #risk stratification
- #early detection
- Early-stage detection is crucial for favorable cancer prognoses.
- Genomics enables detection of tumor-derived DNA in early stages via somatic mutation and methylation patterns.
- Cancer-associated mutations commonly occur in normal tissues, especially with age, but rarely lead to cancer.
- New prognostic frameworks help identify high-risk individuals for early intervention.
- Therapeutic advances improve outcomes, but early detection remains the most important factor.