Long-Term Outcomes of Left Bundle-Branch Pacing vs Biventricular Pacing in Heart Failure: The HeartSync-LBBP Randomized Clinical Trial - PubMed
15 hours ago
- #Heart Failure
- #Clinical Trial
- #Cardiac Pacing
- The HeartSync-LBBP trial compared left bundle-branch pacing (LBBP) and biventricular pacing (BiVP) in 200 heart failure patients with left bundle-branch block (LBBB) and LVEF ≤35%.
- LBBP showed a significantly lower risk of death or heart failure hospitalization (8% vs 28%) compared to BiVP.
- No significant difference in all-cause mortality was observed between LBBP (2.0%) and BiVP (5.0%).
- LBBP significantly reduced the risk of heart failure hospitalization (7.0% vs 28.0%) compared to BiVP.
- Echocardiographic response rates were similar (86.0% vs 81.0%), but super-response rates were higher with LBBP (55.0% vs 36.0%).
- LBBP was superior to BiVP in improving outcomes for patients with LBBB and severely reduced LVEF.