Nanotechnology-mediated strategies for skeletal muscle repair and regeneration: targeted intervention, functional remodeling, and translational challenges - PubMed
3 hours ago
- #Skeletal Muscle Regeneration
- #Targeted Drug Delivery
- #Nanotechnology
- Skeletal muscle is vital for locomotion and metabolism but faces impaired regeneration under pathological conditions, leading to structural and functional damage.
- Current treatments are limited by poor targeting, low bioavailability, and unstable long-term efficacy, necessitating improved therapeutic strategies.
- Nanotechnology offers potential in skeletal muscle repair through drug delivery, scaffolds, nanozymes, and biomimetic engineering for targeted interventions.
- Nanotechnology applications focus on enhancing myogenic differentiation, reducing inflammation and oxidative stress, combating infections and malignancies, and supporting vascularization and neural recovery.
- Clinical challenges and future directions of nanotechnology in skeletal muscle diseases are analyzed to guide research and optimize therapeutic approaches.