The Evolving Landscape of Malaria Prevention Strategies: A Review of Recent Developments - PubMed
6 hours ago
- #malaria
- #prevention
- #vaccine
- Malaria remains a significant global health challenge despite long-term control efforts.
- Barriers to prevention include social inequities, cost constraints, and logistical challenges.
- Current prevention strategies include vector control (insecticide-treated nets, indoor residual spraying), chemoprevention, and immunoprophylaxis.
- Insecticide resistance is compromising the effectiveness of traditional vector control methods.
- Chemoprevention strategies like intermittent preventive treatment in pregnancy and seasonal malaria chemoprevention in children are effective but underutilized.
- Recent vaccine advancements (RTS,S/AS01 and R21/Matrix-M) have shown success in reducing severe disease and mortality.
- Emerging strategies include monoclonal antibodies and genetically modified mosquitoes.
- Challenges include ensuring equitable access, sustaining efficacy, and integrating interventions into diverse health systems.
- Adaptive, multifaceted approaches are needed to achieve malaria elimination goals.