Meta-analysis of genome-wide association studies of food allergy and IgE-sensitization - PubMed
11 hours ago
- #food allergy
- #IgE-sensitization
- #genome-wide association study
- Meta-analysis of genome-wide association studies (GWAS) on food allergy (FA) and IgE-sensitization.
- Study involved 229,426 adults and 14,234 children from 16 European ancestry cohorts.
- Identified 37 SNPs with suggestive significance (p-value < 1x10-6), with two reaching genome-wide significance.
- Highlights genetic differences across FA phenotypes and the need for a unified FA definition.
- Demonstrates shared genetic architecture between FA and other allergies.