Clinical features of chronic inflammatory demyelinating polyneuropathy: a single-center experience with 33 patients - PubMed
6 hours ago
- #IVIg efficacy
- #CIDP variants
- #neuropathy
- Study analyzed 33 CIDP patients at Kumamoto University Hospital (2020-2025).
- 63.6% had CIDP variants (distal: 39.4%, multifocal: 15.2%, motor: 3.0%, sensory: 6.0%).
- Multifocal CIDP had longest diagnostic delays (mean 4.6 years) due to fewer electrophysiological demyelinating signs.
- Typical CIDP showed lowest MRC sum scores, indicating greater severity.
- IVIg was highly effective across all subtypes, including multifocal CIDP (contrary to prior reports).
- 78.8% required maintenance therapy (IVIg/corticosteroids most common) over 5.1-year mean follow-up.
- No subtype transitions observed during follow-up.