Resetting autoimmune disease with CAR cell therapies - PubMed
3 hours ago
- #Autoimmune Diseases
- #CAR T cells
- #B Cell Depletion
- CAR cell therapies are being developed to reset the immune system in autoimmune diseases by depleting pathogenic B cells.
- The review discusses deep B cell depletion, targets like CD19 and BCMA, and the use of autologous and allogeneic CAR T cells.
- It covers current evidence on efficacy, safety, risks, limitations, and future technological and clinical developments for treating autoimmune diseases.