Extracellular CD44 lactylation impairs CD8+ T cell function in KRAS-mutant colorectal cancer - PubMed
12 hours ago
- #KRAS mutation
- #colorectal cancer
- #CD8+ T cells
- Extracellular CD44 lactylation negatively affects CD8+ T cell function in KRAS-mutant colorectal cancer.
- Authors H.W., Y.-X.L., and Y.Y. have a pending patent related to this research.
- Funding was provided by multiple grants from the National Natural Science Foundation of China and the Natural Science Foundation of Jiangsu Province.