Innate immunity in allergic diseases: Novel concepts - PubMed

4 hours ago

Innate immunity is recognized as a key driver in the initiation and persistence of allergic diseases, offering potential as biomarkers and therapeutic targets.
The review covers molecular mechanisms where innate immune cells interact with adaptive immunity to promote type 2-mediated allergic diseases, such as asthma and atopic dermatitis.
Trained immunity and maladaptive trained immunity are emerging factors that can either protect against or promote the development of allergic diseases.
Understanding innate immune pathways and their interplay with adaptive immunity may lead to novel biomarkers, therapeutic targets, and precision medicine approaches to reduce the socioeconomic burden of allergic diseases.

Hasty Briefsbeta