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A Retrospective Observational Study of Safety and Effectiveness of Abemaciclib in Chinese Patients with Breast Cancer - PubMed

10 hours ago
  • #treatment safety
  • #real-world evidence
  • #breast cancer
  • Abemaciclib demonstrated a well-tolerated safety profile with adverse events mostly of grades 1-2, with neutropenia being the most common in Chinese patients with breast cancer.
  • Effectiveness analysis among advanced breast cancer patients showed that 12-month real-world progression-free survival and overall survival rates varied by therapy line, being highest in first-line treatment.
  • The study confirms abemaciclib's positive benefit-risk profile in real-world clinical practice, aligning with findings from prior clinical trials, and shows consistency across different patient subgroups.