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Vascular Health After Quitting Smoking or Switching to E-Cigarette Use: A Systematic Review of Prospective Studies with GRADE Assessment - PubMed

6 hours ago
  • #e-cigarettes
  • #vascular health
  • #smoking cessation
  • Systematic review evaluates effects of smoking cessation or switching to e-cigarettes on vascular health.
  • 23 studies with 11,702 participants included, showing improvements in vascular function markers like PWV, AIx, and FMD.
  • Improvements observed within one month and sustained up to 24 months post-cessation.
  • Certainty of evidence varied from very low to moderate, with RCTs on FMD showing moderate certainty.
  • E-cigarettes showed potential benefits for vascular function, but long-term effects remain uncertain.
  • Combustion, not nicotine, may be the primary driver of vascular impairment.
  • More robust, long-term studies needed to confirm findings.