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Guidelines for the management of Helicobacter pylori infection in Japan: 2024 revised edition - PubMed

5 hours ago
  • #Gastric Cancer
  • #Helicobacter pylori
  • #Guidelines
  • The Japanese Society for Helicobacter Research (JSHR) published the 2024 revised edition of H. pylori management guidelines in Japanese.
  • All H. pylori infectious diseases remain indications for eradication, with no change in this basic policy.
  • Nucleic acid amplification was added as a new diagnostic method, and the effects of proton-pump inhibitors (PPIs) on diagnostic tests were updated.
  • Potassium-competitive acid blockers are superior to PPIs in 1-week triple therapy with amoxicillin and clarithromycin.
  • A flowchart for eradication therapy was provided for use in real-world clinical settings.
  • For gastric cancer prevention, earlier age eradication is recommended, and strategies for adolescents are described.
  • Some clinical questions on gastric cancer prevention were identified, but evidence was insufficient for recommendations based on clinical importance.