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Machine learning-based estimation of trunk fat percentage and its association with cardiometabolic risk leveraging two large national cohorts - PubMed

3 months ago
  • #trunk fat percentage
  • #machine learning
  • #cardiometabolic risk
  • Developed and validated a machine learning model to estimate trunk fat percentage using anthropometric measures.
  • Utilized data from NHANES (n=30,443) for development and CHARLS (n=13,524) for external validation.
  • XGBoost model showed superior performance with R² of 0.8509 on the test set.
  • Simplified model with five variables (sex, waist circumference, height, weight, age) retained 99.3% accuracy.
  • Trunk fat percentage outperformed whole-body fat percentage in predicting cardiometabolic risks.
  • Highest AUC improvement observed for diabetes (3.22% relative improvement).
  • Average relative improvement in AUC across all endpoints was 2.77%.
  • Provides a non-invasive tool for central adiposity assessment in clinical and epidemiological studies.