Healing the heart naturally: The role of bioactive phytocompounds in cardiovascular therapeutics - PubMed
6 hours ago
- #Natural Therapeutics
- #Phytocompounds
- #Cardiovascular Health
- Cardiovascular diseases are the leading cause of death globally, driving interest in plant-based treatments due to limitations of conventional therapies.
- Bioactive phytocompounds like curcumin, resveratrol, and berberine show cardioprotective effects by reducing oxidative stress and inflammation, improving endothelial function, and regulating lipid metabolism.
- These compounds work through molecular mechanisms involving nitric oxide, calcium signaling, NF-κB, and MAPK pathways, and also influence gut microbiota metabolites.
- Nanotechnology-based delivery systems enhance the effectiveness and specificity of phytocompounds for cardiovascular applications.
- Clinical evidence supports the efficacy of phytocompounds in conditions such as hypertension, atherosclerosis, and heart failure, but further standardization and trials are needed for integration into mainstream medicine.