Effect of platelet-rich plasma in refractory vitiligo by promoting the differentiation of dermal melanocyte progenitors via IGFBP-2/RhoA/YAP pathway - PubMed
12 hours ago
- #vitiligo
- #melanocyte differentiation
- #platelet-rich plasma
- PRP combined with 308-nm excimer phototherapy improves repigmentation in acral vitiligo.
- Pigment index improvements were observed in various areas, including palms and fingers.
- PRP activates dermal melanocyte progenitors (DMPs) via the IGFBP-2/RhoA/YAP pathway.
- IGFBP-2 was identified as a key effector in PRP for melanocyte differentiation.
- The study supports PRP as a promising therapeutic strategy for treatment-resistant vitiligo.