Association of inflammatory bowel disease with cardiovascular disease, and the mediating role of inflammation: a matched-cohort study - PubMed
6 hours ago
- #cardiovascular disease
- #inflammation
- #inflammatory bowel disease
- The study found an increased risk of cardiovascular disease (CVD) in patients with inflammatory bowel disease (IBD).
- IBD was associated with higher risks of specific CVD entities including ischemic heart disease, heart failure, arrhythmias, atrial fibrillation, other supraventricular arrhythmia, and venous thromboembolism.
- Inflammatory biomarkers were found to mediate the association between IBD and CVD, with a higher mediation proportion observed in Crohn’s disease compared to ulcerative colitis or IBD-unclassified.
- The study suggests that reducing inflammation may help lower the cardiac burden in patients with IBD.
- The research utilized data from the UK Biobank, including 1494 IBD patients and 14,940 matched reference individuals.