Subcellular calcium dynamics and organelle perturbations in resistosome-mediated cell death - PubMed
5 hours ago
- #organelle disruption
- #calcium dynamics
- #NLR proteins
- Plant NLR proteins form resistosomes to execute immune responses.
- NRC4 resistosome activation leads to calcium influx and membrane enrichment.
- Mitochondria and plastid disruption occur first, followed by ER fragmentation and cytoskeleton depolymerization.
- Plasma membrane integrity loss, nuclear shrinkage, and vacuolar collapse mark terminal cell death.
- Study provides spatiotemporal insight into plant immune cell death mechanisms.