The relationship between triglyceride-glucose index, triglyceride-glucose-body mass index, and the severity of hepatic steatosis and liver fibrosis in patients with MASLD: a cross-sectional study - Pu
6 hours ago
- #liver fibrosis
- #TyG-BMI index
- #MASLD
- The study investigates the relationship between TyG index, TyG-BMI index, and severity of hepatic steatosis and liver fibrosis in MASLD patients.
- A retrospective analysis of 7,035 subjects undergoing Fibrotouch testing was conducted.
- Both TyG and TyG-BMI indices showed significant positive correlation with MASLD severity, with TyG-BMI showing stronger association.
- TyG-BMI's highest quartile had a 239.41-fold higher risk of hepatic steatosis compared to the lowest quartile.
- For liver fibrosis, only TyG-BMI maintained an independent association.
- ROC analysis indicated TyG-BMI's superior predictive performance for MASLD over TyG index (AUC: 0.908 vs. 0.774).
- TyG-BMI index is concluded to be a strong predictor of MASLD severity and liver fibrosis, outperforming the traditional TyG index.