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Clinical features of adolescent-onset functional motor disorders in tertiary movement disorders centers - PubMed

5 hours ago
  • #Adolescent Neurology
  • #Functional Motor Disorders
  • #Movement Disorders
  • Adolescent-onset Functional Motor Disorders (FMDs) are common but often misdiagnosed, leading to delays in treatment.
  • The study analyzed 847 patients from the Italian Registry of FMDs, with 93 (10.9%) having adolescent-onset FMDs.
  • Adolescent-onset FMDs showed similar motor phenotypes to adult-onset FMDs, except for parkinsonism, which was only observed in adults.
  • Adolescent-onset FMDs were associated with longer disease duration, more medical consultations, and higher frequency of functional seizures and infections.
  • Adolescents with FMDs had lower rates of insomnia, fatigue, and antipsychotic use compared to adults.
  • Pain was more commonly associated with combined FMDs phenotypes.
  • Early and accurate diagnosis of adolescent-onset FMDs can reduce unnecessary investigations and inappropriate treatments.