Sarcopenia as a risk factor for nonalcoholic fatty liver disease and liver fibrosis: an updated systematic review and meta-analysis - PubMed

5 hours ago

Sarcopenia is linked to a higher prevalence in NAFLD populations compared to non-NAFLD controls (23% vs. 15%).
Meta-analysis shows sarcopenia increases the risk of NAFLD by 1.58-fold and liver fibrosis by 2.03-fold.
Subgroup analyses indicate variability in association strength based on NAFLD diagnostic methods, with CT-based diagnosis showing the highest risk association.
The study highlights the need for standardized diagnostic criteria and longitudinal studies to establish causality between sarcopenia and NAFLD/liver fibrosis.

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