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A phase II study evaluating pharmacokinetics and dosimetry of 177Lu-PSMA-617 radioligand therapy in Chinese participants with progressive metastatic castration-resistant prostate cancer - PubMed

5 hours ago
  • #Pharmacokinetics
  • #Prostate Cancer
  • #Radioligand Therapy
  • Phase II study on 177Lu-PSMA-617 radioligand therapy in Chinese patients with metastatic castration-resistant prostate cancer.
  • Study focused on pharmacokinetics, biodistribution, and organ dosimetry of the therapy.
  • Compliance with Declaration of Helsinki and Good Clinical Practice Guidelines.
  • Ethical approval obtained from multiple Chinese medical institutions.
  • Informed consent was secured from all participants, with data deidentified for publication.
  • Some authors are employees of Novartis Pharmaceuticals and hold Novartis stock.
  • References include global and Chinese cancer statistics and trends.
  • Systematic review on PSMA-targeted imaging and radioligand therapy mentioned.