New developments and applications of human organoids - PubMed
3 hours ago
- #stem cells
- #organoids
- #disease modeling
- Organoid technology enables in vitro study of human biology and disease using self-organizing 3D structures from stem cells.
- Organoids offer advantages over classical cell lines by modeling disease mechanisms, personalized therapies, and tissue heterogeneity.
- Limitations exist as current organoids are reductionist and do not fully capture human tissue complexity.
- Next-generation organoid models aim to improve cellular interactions, tissue architecture, and microenvironmental representation.
- Applications focus on human tissue stem cell-derived organoids, with clinical translation innovations.