Prophylactic clipping after colorectal endoscopic submucosal dissection in randomized controlled trials: a systematic review and meta-analysis - PubMed
5 hours ago
- #endoscopic submucosal dissection
- #prophylactic clipping
- #colorectal polyps
- Prophylactic clipping after colorectal endoscopic submucosal dissection (ESD) significantly reduces the risk of clinically significant delayed bleeding (0.3% vs. 3.4%).
- No significant differences were found for postprocedural perforation (PPP) or postelectrocoagulation syndrome (PECS) between clipping and no clipping groups.
- Subgroup analyses by lesion size (>30 mm vs. <30 mm) and location (proximal vs. distal colon) showed no significant differences.
- The study supports the adoption of prophylactic clipping in routine practice due to a 74% decrease in delayed bleeding risk.
- The meta-analysis included four randomized controlled trials (RCTs) from Asia, involving 684 patients.