Objective Memory Impairment in Post-Traumatic Stress Disorder: a Systematic Review and Multilevel Meta-Analysis of Trauma-Exposed Adult Populations - PubMed
5 hours ago
- #memory impairment
- #PTSD
- #meta-analysis
- PTSD is traditionally seen as a disorder of fear learning and emotional dysregulation, but evidence shows objective cognitive dysfunction, especially memory impairment, is a core feature.
- This systematic review and meta-analysis aimed to determine if trauma-exposed adults with PTSD show objective memory impairments compared to those without PTSD.
- The study included a comprehensive search of multiple databases up to December 17, 2025, focusing on trauma-exposed adults with PTSD diagnosed via DSM or ICD criteria.
- Results from 88 studies showed individuals with PTSD had significantly poorer memory performance, particularly in verbal episodic memory and working memory.
- The findings support PTSD as a disorder involving maladaptive memory processing and highlight the need for cognitive assessment and intervention in PTSD care.