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Evaluation of Supracardiac Atherosclerosis in Stroke with a Noncontrast Head-Neck-Aortic Vessel Wall MRI - PubMed

6 hours ago
  • #MRI
  • #stroke
  • #atherosclerosis
  • Supracardiac atherosclerosis is a major cause of stroke.
  • A noncontrast head-neck-aortic vessel wall MRI (vwMRI) protocol was developed with neural network-based acceleration and multichannel coils, achieving a scan time of ~15 minutes.
  • 108 participants with acute ischemic stroke or transient ischemic attack underwent both vwMRI and supra-aortic CT angiography (CTA).
  • vwMRI showed a higher plaque detection rate (81.5%) compared to CTA (69.4%).
  • vwMRI achieved 91% accuracy in detecting calcification, identified intraplaque hemorrhage in 27.8% of participants, and showed comparable ulceration rates to CTA.
  • vwMRI helped reclassify 16 out of 38 participants initially diagnosed with embolic stroke of undetermined source (ESUS), reducing ESUS cases from 35.2% to 20.4%.
  • The study concluded that the vwMRI protocol is feasible and outperforms CTA in plaque detection.