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Lecanemab and Donanemab Combination Therapy for Alzheimer's Disease-The Cocktail May Work Even Better Together - PubMed

6 hours ago
  • #Alzheimer's disease
  • #combination therapy
  • #antiamyloid immunotherapy
  • Lecanemab and Donanemab are FDA-approved antiamyloid immunotherapies for Alzheimer's disease.
  • Lecanemab targets amyloid protofibrils, while Donanemab targets amyloid plaques intracranially.
  • Combination therapy of both drugs may produce an augmented effect.
  • Research on combination therapy requires collaboration between pharmaceutical companies, academia, government, and advocacy groups.