Drug-Related Uveitis: A Real-World Study Based on the Food and Drug Administration Adverse Event Reporting System Database - PubMed
6 hours ago
- #FAERS database
- #drug-related uveitis
- #adverse drug events
- Study analyzes drug-related uveitis (DRU) using FDA Adverse Event Reporting System (FAERS) data from 2004-2024.
- 39 drugs linked to DRU, including antineoplastic agents, ophthalmic drugs, antibiotics, and others.
- Top high-risk drugs: faricimab (ROR=151.07), pegcetacoplan (ROR=130.51), rifabutin (ROR=103.40).
- Antibiotics have the shortest drug-induced onset time (mean=20.55 days).
- DRU predominantly affects females (59.43%) and the elderly (average age=52.23±20.92 years).
- Increasing trend in DRU cases over the past 20 years.
- Prevention of DRU is emphasized over treatment; risk identification can help avoid occurrences.