Global, regional, and national trends in mortality and disability attributable to elevated fasting plasma glucose in Alzheimer disease and other dementias, 1990-2021 - PubMed
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- Study assessed trends in Alzheimer's disease (AD) and other dementias attributable to elevated fasting plasma glucose (FPG) from 1990 to 2021 using Global Burden of Disease (GBD) data.
- Global age-standardized mortality rate and years lived with disability (YLDs) for dementia due to elevated FPG increased annually by 1.1% and 1.2%, respectively.
- Females showed a numerically greater average annual increase in dementia burden attributable to elevated FPG compared to males, with rates rising progressively with age.
- Countries with higher sociodemographic index (SDI) scores had a slower increase in burden, but this association was not statistically significant.
- Findings highlight the growing impact of dementia linked to elevated FPG and underscore the importance of addressing metabolic risk factors in public health strategies.