Slow-Release Oral Morphine vs Methadone for Opioid Use Disorder in the Fentanyl Era - PubMed
5 hours ago
- #opioid use disorder
- #slow-release oral morphine
- #methadone
- The study compares slow-release oral morphine (SROM) and methadone for treating opioid use disorder (OUD) in the fentanyl era.
- Participants were adults aged 19-65 with OUD in British Columbia, Canada, from 2017 to 2024.
- SROM showed a slightly higher risk of treatment discontinuation and lower adherence compared to methadone.
- Mortality risks were similar between SROM and methadone treatments.
- Both medications may be appropriate if retention support measures are in place.