Associations of Lifetime Cognitive Enrichment With Incident Alzheimer Disease Dementia, Cognitive Aging, and Cognitive Resilience - PubMed
3 months ago
- #Alzheimer's disease
- #Cognitive resilience
- #Cognitive enrichment
- Lifetime cognitive enrichment is associated with a 38% lower risk of developing Alzheimer's disease (AD) dementia.
- High lifetime cognitive enrichment delays the onset of AD dementia by an average of 5 years compared to low enrichment.
- Cognitive enrichment is linked to better baseline cognitive function and slower cognitive decline, even after adjusting for AD-related pathologies.
- The study found no significant associations between lifetime cognitive enrichment and neuropathologic indices of AD and related dementias (ADRD).
- Cognitive resilience, or the ability to maintain cognitive function despite pathology, is higher in individuals with greater lifetime cognitive enrichment.