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Move over, AlphaFold: open-source model predicts shape of 1B proteins

6 hours ago
  • #Bioinformatics
  • #Protein Structure
  • #Artificial Intelligence
  • ESM Atlas released with over 1 billion predicted protein structures and 6.8 billion sequences using AI tool ESMFold2.
  • ESMFold2 outperforms AlphaFold3 in predicting protein complexes, including antibody-antigen interactions, and is fully open source.
  • Atlas includes metagenomic sequences from environments like soil and ocean, revealing new biological connections, such as similarities between CRISPR proteins and a fungal gene-editing protein.