Predictors of severe coronary involvement in children with Kawasaki disease: a single-centre cohort study - PubMed

4 hours ago

Severe Kawasaki disease was defined by a baseline coronary Z-score ≥5.0 and occurred in 9.6% of patients in the single-centre cohort study.
Predictors of severe coronary involvement included delayed intravenous immunoglobulin treatment and baseline pericardial effusion, while higher serum albumin levels were protective.
Severe cases were younger, had longer diagnostic delays, prolonged fever, and showed associations with hypoalbuminaemia, anaemia, thrombocytosis, and delayed inflammatory resolution.
Coronary Z-scores declined during follow-up in severe cases, but 60% had persistent abnormalities, emphasizing the importance of early recognition and timely treatment.

Hasty Briefsbeta