Early-Onset Obesity and Heart Failure Burden Independent of Cardiometabolic Risk Factors - PubMed
3 hours ago
- #cardiovascular risk
- #early-onset obesity
- #heart failure
- Timing of obesity onset affects long-term cardiovascular risk, with early-onset obesity beginning around age 25.
- Study of 19.4 million U.S. adults with obesity from NHANES 2017-2020, including 2.56 million with early-onset obesity.
- No differences in adjusted cardiometabolic measures between early-onset and adult-onset obesity groups.
- Congestive heart failure (CHF) more common with early-onset obesity (13.5% vs. 6.6%).
- Adult-onset obesity linked to lower odds of CHF (adjusted OR: 0.43, 95% CI: 0.23-0.82).
- No significant differences observed for coronary heart disease, angina, myocardial infarction, stroke, or hard cardiovascular disease.
- Early-onset obesity associated with higher CHF burden, suggesting cumulative obesity exposure may influence heart failure development.