HSP27 functional switch drives castration-resistant prostate cancer via mTOR pathway activation, highlighting promising combination therapies - PubMed
8 hours ago
- #Castration-resistant prostate cancer
- #HSP27
- #mTOR pathway
- HSP27 undergoes a functional switch to drive castration-resistant prostate cancer (CRPC) progression.
- Activation of the mTOR pathway by HSP27 is a key mechanism in CRPC development.
- Combination therapies targeting HSP27 and mTOR show promise for treating CRPC.