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Histone methyltransferase EZH2 drives podocyte injury and senescence in diabetic nephropathy through STAT3 activation - PubMed

14 hours ago
  • #STAT3
  • #EZH2
  • #Diabetic nephropathy
  • EZH2 histone methyltransferase contributes to podocyte injury and senescence in diabetic nephropathy via STAT3 activation.
  • The study was approved by the Institutional Ethics Committee of the First Affiliated Hospital of Zhengzhou University (Ethics Approval No. 2023-KY-0656-002).
  • Animal procedures were approved by the Institutional Animal Care and Use Committee (ZZU-LAC20220722 [19]).
  • The authors declare no conflicts of interest.
  • References include global diabetes prevalence estimates and updates on diabetic nephropathy diagnosis, prognosis, and treatment.