Cardiometabolic index (CMI) and sarcopenia as predictors of all-cause and cardiovascular mortality in chronic kidney disease: a NHANES-based cohort study - PubMed
4 hours ago
- #Mortality Risk
- #Cardiometabolic Health
- #Chronic Kidney Disease
- The study investigates the impact of Cardiometabolic Index (CMI) and sarcopenia on all-cause and cardiovascular mortality in CKD patients.
- Data from NHANES (1999-2006, 2011-2018) included 1,886 CKD patients analyzed using Kaplan-Meier, Cox models, and ROC analysis.
- Patients with high CMI and sarcopenia had the lowest survival rates.
- Highest CMI quartile showed significantly increased risks: all-cause mortality (HR=2.25) and cardiovascular mortality (HR=4.03).
- Sarcopenia independently increased risks for all-cause (HR=1.27) and cardiovascular mortality (HR=1.12).
- Nonlinear relationships were found between CMI and mortality, irrespective of sarcopenia status.
- CMI and sarcopenia are prognostic biomarkers for mortality risk stratification in CKD.