The 2025 International Consensus Meeting on Musculoskeletal Infection: Research Priorities and Future Directions - PubMed
5 hours ago
- #anti-biofilm strategies
- #research priorities
- #musculoskeletal infection
- The 2025 International Consensus Meeting (ICM) focused on musculoskeletal infection (MSKI), a major cause of implant failure with severe outcomes.
- Key research priorities identified include improving diagnostics via standardized sampling, advanced imaging, and biofilm-specific biomarkers.
- Developing clinically relevant in-vitro and in-vivo models to test antibiofilm strategies effectively is a critical area.
- High-priority immunological research involves understanding T-cell immunity in biofilm persistence and potential T-cell targeting therapies.
- Clinical evaluation of novel anti-biofilm technologies in larger patient cohorts is needed for validation.
- Addressing translational barriers through multi-center data collection and large-scale data tools aims to accelerate clinical applications.