In situ structures of the portal-neck-tail complex of bacteriophage T4 inform a viral genome positioning mechanism - PubMed
10 hours ago
- #bacteriophage T4
- #cryo-EM
- #viral assembly
- Study reveals in situ structures of the portal-neck-tail complex in bacteriophage T4.
- Identifies a genome positioning mechanism post-packaging, involving conformational changes in the portal structure.
- Highlights the role of pressure in genome movement and positioning within the virion.
- Details how the genome is poised for ejection into a host cell upon signal.
- Findings contribute to understanding viral assembly and genome delivery mechanisms.