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Cognitive Decline in Atherosclerotic Diseases: Mechanisms and Potential Solutions - PubMed

3 days ago
  • #Cognitive Decline
  • #Atherosclerosis
  • #Vascular Dementia
  • Atherosclerosis contributes to cognitive decline via cerebral hypoperfusion, oxidative stress, and chronic inflammation.
  • Shared risk factors like hypertension and diabetes exacerbate neurovascular dysfunction, increasing dementia susceptibility.
  • Advances in neuroimaging and biomarkers enhance early detection and intervention for vascular-related cognitive impairment.
  • Preventive strategies, including lifestyle changes, statins, and cognitive rehabilitation, can mitigate cognitive deterioration.
  • A multidisciplinary approach integrating cardiovascular and neurological care is essential for improved outcomes.
  • Future research should focus on refining diagnostics and targeting high-risk individuals to reduce global dementia burden.