Prognostic Factors for Long-Term Risk of Stroke After Transient Ischemic Attack or Minor Stroke: A Systematic Review and Meta-Analysis - PubMed
6 hours ago
- #TIA
- #stroke risk
- #meta-analysis
- Patients with transient ischemic attack (TIA) or minor stroke face an increased long-term risk of subsequent stroke, lasting at least 10 years.
- A systematic review and meta-analysis identified 28 cohort studies involving 86,810 patients to evaluate prognostic factors for long-term stroke risk.
- High certainty evidence links several factors to increased stroke risk, including older age, male sex, atrial fibrillation, diabetes mellitus, hypertension, ischemic heart disease, prior stroke/TIA history, smoking, ABCD2 score ≥4, acute infarct on neuroimaging, minor stroke as the index event, and specific stroke subtypes like cardioembolism, large artery atherosclerosis, and small vessel disease.
- The study highlights the importance of identifying high-risk patients for targeted monitoring and treatment to prevent future strokes.
- Population attribution fractions (PAF) were calculated to estimate the impact of each factor on the overall stroke risk in this patient population.