Cardiogenic Shock Revisited: From Hemodynamic-Centric to Multimodal Precision Care - PubMed
5 hours ago
- #Cardiogenic shock
- #Multimodal diagnosis
- #Precision care
- Cardiogenic shock (CS) remains a major clinical challenge with high short-term mortality despite advances in treatment.
- Traditional hemodynamic-centric approaches have not significantly improved outcomes.
- CS involves inflammatory activation, microcirculatory dysfunction, endothelial injury, and metabolic derangements.
- Multimodal diagnostic approaches (microcirculation assessment, omics-based phenotyping, advanced echocardiography, AI risk stratification) may improve early recognition and classification.
- Reframing CS as a dynamic, multisystem disorder supports a shift toward precision care.