Assessment and Incidence Determination of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Following a SARS-CoV-2 Infection in a Prospective Cohort of Hospital Employees - PubMed
5 hours ago
- #Healthcare Workers
- #Post-COVID-19 Syndrome
- #Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
- The study assessed the incidence of Post-COVID-19 Syndrome (PCS) with fatigue and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) in hospital employees following SARS-CoV-2 infection.
- Of 221 hospital employees who tested positive for SARS-CoV-2, 11.8% reported persistent fatigue, and 3.2% were diagnosed with ME/CFS based on Canadian Consensus Criteria.
- Assessments of 19 participants showed 42.1% had below-normal cognitive scores, 66.6% had increased autoantibodies against GPCRs, and 86.7% showed possible EBV reactivation.
- The study suggests that EBV reactivation, increased GPCR autoantibodies, and coagulation changes may contribute to the pathogenesis of PCS and ME/CFS.
- It establishes a diagnostic pathway and highlights occupational risks for healthcare workers with nosocomial infections.