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Hydrochlorothiazide and chlorthalidone use and glaucoma risk: pharmacovigilance analysis and nationwide cohort study - PubMed

6 hours ago
  • #glaucoma risk
  • #diuretics
  • #pharmacovigilance
  • Pharmacovigilance analysis of FAERS suggests a potential association between hydrochlorothiazide/chlorthalidone and glaucoma.
  • A nationwide cohort study in Korea finds no significant increased risk of overall glaucoma from hydrochlorothiazide or chlorthalidone use.
  • Higher cumulative doses of hydrochlorothiazide may be linked to a modest increase in glaucoma risk, but chlorthalidone shows no clear dose-response relationship.