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Deciphering mechanical determinants of morphological evolution - PubMed

5 hours ago
  • #morphogenesis
  • #mechanobiology
  • #evo-devo
  • The study explores how mechanical forces influence morphological diversity across species.
  • Researchers analyzed six cnidarian species to identify mechanical modules (mechanotypes) that predict larval shapes.
  • Shape elongation is determined by a single mechanical module, while shape polarity depends on multiple modules.
  • Perturbations mimicking regulatory differences between species can reprogram larval morphology to resemble other species.
  • The findings provide a mesoscale mechanical framework for understanding how tissue-scale parameters generate morphological diversity.