The multi-omics landscape of lung adenocarcinoma evolution: deciphering metabolic reprogramming-driven immune escape and its implications in combined therapy - PubMed
6 hours ago
- #immune escape
- #lung adenocarcinoma
- #metabolic reprogramming
- Review explores the multi-omics landscape of lung adenocarcinoma evolution, focusing on metabolic reprogramming-driven immune escape.
- Highlights mechanisms where cancer cells impair immune function via nutrient deprivation and oncometabolites causing epigenetic modifications.
- Discusses development of early-screening biomarkers from metabolic signatures and combination therapies targeting dual metabolic-immune checkpoints.